Leucas is a genus of plants in the family lamiaceae, first described by robert brown in 1810. Leucas aspera is reported to have antifungal, prostaglandin inhibitory, antioxidant, antimicrobial, antinociceptive and cytotoxic activities. Thus the new name for the family labiatae became lamiaceae. Leucas aspera, diuretics activity, lipchitz method, laxative activity, furosemide, agaragar. Studies on larvicidal and pupicidal activity of leucas. The activityguided repeated fractionation of the methanol extract by silica gel column chromatography yielded a compound that. This study was undertaken to investigate diuretic and laxative potency of leucas aspera whole plant. If you would like to support this site, please consider donating. Investigation of the inhibitory fraction of leucas aspera on prostaglandininduced contraction in guinea pig ileum provided four new diterpenes, leucasperones a 1 and b 2 and leucasperols a 3 and b 4, and three new isopimarane glycosides, leucasperosides a, b, and c 5. However, free flavonoid baicalein was reported in the ethereal fraction of hydro methanolic extract of leucas. Vijayaraj and swarnakala department of marine biotechnology, amet university, kanathur, chennai 603112, tamilnadu, india. Plant details information about leucas aspera plant.
Conventionally, it is also used as an antipyretic and insecticide. The free radical scavenging activity of the methanol and aqueous extracts of leucas aspera leaves, based on the scavenging activity of the stable free radical 1,1 diphenyl2 picrylhydrazyl dpph were determined by mixing of 0. It also strongly inhibited the peroxidation of lipids. The aim of this study was to explicate antibacterial, antifungal, and antioxidant activities of leucas aspera flowers. Jul 09, 2019 antimicrobial activity of leucas aspera pdf both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. The mode of antimicrobial action of the essential oil of melaleucaalternifolia tea tree oil. Introduction excessive amounts of these free radicals can. This plant is an annual herb commonly found at roadsides and. It is pungently aromatic and commonly used as an antipyretic herb in south india. Pdf leucas aspera commonly known as thumbai is distributed throughout india from the. Phytochemicals can play the role to scavenge these excess free radicals.
A novel phenolic compound from leucas aspera spreng. As of march 2014 the plant list recognises 3 accepted species including. Introduction excessive amounts of these free radicals can lead to cell injury and death, which results in many diseases such as cancer, stroke. Pharmacological and medicinal uses of achyranthes aspera saba hasan amity institute of biotechnology, amity university, lucknow u. The scavenging activity of these extracts was lower compared with both antioxidants, bht to evaluate antioxidant, antimicrobial and cytotoxic activity of different parts root, flower, leaf and. In sri lanka, six species exist with leucas zeylanica l. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 111632 with original publication details.
Media in category leucas aspera the following 95 files are in this category, out of 95 total. The plant is used traditionally as an antipyretic and insecticide. Introduction leucas aspera belonging to the family labiate is wellknown for its wide medicinal applications fig. Leucas aspera nanomedicine shows superior toxicity and cell. Leucas aspera is a plant species within the genus leucas and the family lamiaceae. It was selected for purification of the bioactive compound. Phytol a chemical constituent of leucas aspera through. Leaves sub sessile, linearlanceolate, obtuse, and entire.
The free radical scavenging and antioxidant activity of petroleum ether, ethanol, isopropyl alcohol, ethyl acetate and chloroform extracts of l. Antioxidant properties of a novel flavonoid from leaves of. Isolation and identification of nicotine from leucas aspera willd indian j pharm sci. Methanolic extract of whole plant exhibited dpph free radical scavenging. Ts of leaf passing through the midrib is broadly convex on the lower side and slightly grooved or flat on the upper side, a centrally located conjoint and collateral meristele associated with a parenchymatous pericycle layer on lower side, collenchymatous tissue underneath both the. Preliminary chemical examination of some compounds in the different parts of the genus leucas. Leucas species leucas aspera name synonyms leucas dimidiata roth spreng. Antioxidant anticancer activity of leucas aspera extract and. Leucas aspera, is a herb is widely distributed in tropical asia, africa and grows in highland crop fields, homesteads, fallow lands and roadsides3. Elemental analysis of leucas aspera semantic scholar. Leucas aspera belongs to the family lamiaceae commonly known as. Aiton, locally known as gatathumba, as most widely distributed species. Plants are being used from more than years to treat diseases. Aiton is a popular, multipurpose medicinal plant in sri lanka but the pharmacological potential and the chemical profile have not been systematically investigated to understand and rationalize the reported ethnobotanical significance.
Studies on larvicidal and pupicidal activity of leucas aspera. Title plant resources of southeast asia publication author. Plant tissue culture has paved way for the production of both pathogenfree plants and secondary metabolites in large scale. Leucas aspera is an annual, branched, herb erecting to a height of 1560 cm with stout and hispid acutely quadrangular stem and branches. Leaves are subsessile or shortly petiolate, linear or linearly lanceolate, obtuse, pubescent up to 8. Pharmacognostic and in vitro anti diabetic activity on. It has many vernacular names depending on the region and most commonly known as thumbai. In vitro antidiabetic activity of polar and nonpolar solvent. It is a small erect, much branched annual herb grows up to 60 cm in height.
Lamiaceae labiatae according to the rules of icbn the names of the families should end in aceae. Leucas aspera, leucas zeylanica, antifungal, dermatophytes. The healing properties of plants have been transferred within the human communities for over the centuries. The plant, leucas aspera willd link is well known for its varied medicinal uses. Pelagia research library procured from raj biotech india pvt. In vitro antidiabetic activity of polar and nonpolar. Leucas aspera, antioxidant, free radical and cytotoxicity 1.
Herbal medicines are widely used since time immemorial indicating that herbs are a growing part of modern, hightech medicine. Many plants and herbs hold their prestigious position in the field of medicine. Leucas aspera is an erect, annual plant with a muchbranched stem 30 60cm tall310. Acute toxicity study was carried out for fresh juice of leaves of leucas aspera with doses 2, 4. Jun 08, 2011 it is a small erect, much branched annual herb grows up to 60 cm in height. Acute toxicity study was carried out for fresh juice of leaves of leucas aspera with doses 2, 4 and 6mlkg with water. In evaluation of diuretic activity male albino rats were used as the experimental animals. Herbal medicine is one of the oldest valuable bestowals that was given to mankind. Leucas aspera is widely use d as foods and also for nutr itional requirement in countryside which was reported to have high protein content of 21. Pharmacognostic and in vitro anti diabetic activity on aerial.
Leucas aspera commonly known as thumbai, gumma is found all over india. Narasimhan, centre for floristic research, department of botany, madras christian college, tambaram. The present study was aimed to evaluate the antidiabetic and antioxidant activity of polar and nonpolar solvent extracts of leucas aspera willd. Leucas aspera commonly known as thumbai is widely distributed throughout india from the himalayas down to ceylon. Spray early in the morning on infested plant parts. The dried whole plant leaves, stems, and flowers material was subjected to extraction by continuous hot percolation method. This file is licensed under the creative commons attributionshare alike 4. Diterpenes from leucas aspera inhibiting prostaglandin. Last update on medicinxl wikipedia, the free encyclopedia. They were properly washed in tap water and rinsed in distilled water and dried in an oven at a temperature of 35 40 0 c for 3 days and pulverized using a mortar and. The whole plant is used for different medicine in ayurveda thumba is a flower of kerala,it signifies purity. Among the four regions, leucas aspera from jagityala region contains more phenolic content 48. Phytochemical evaluation and in vitro antioxidant activity. The plant is used to treat many diseases such as cough,cold diarrhea,inflammatory diseases.
Diterpenes from leucas aspera inhibiting prostaglandininduced contractions. Phytol a chemical constituent of leucas aspera through hptlc. Structure of leucasin isolated from leucas aspera leaves. Leucas aspera nanomedicine shows superior toxicity and. In the present study, leaves of leucus aspera were collected from kollam in kerala, and its methanolic extraction was prepared. Leucas revealed the presence of tannins, alkaloids and glycosides ramya et al. Although the species has many different common names depending on the region in which it is located, it is most commonly known as thumbai malayalam. Chemical composition, in vitro antimicrobial, freeradicalscavenging and antioxidant activities of the. Leucas aspera at gandipet, hyderabad, ap w2 img 9054. It contains over 200 species, widespread over much of africa, and southern and eastern asia iran, india, china, japan, indonesia, etc.
Link is an accepted name this name is the accepted name of a species in the genus leucas family lamiaceae. Leucas aspera material was collected from gangapur dam, nasik, maharashtra, india. A total of species belo hedge leucas capitata desf. The juice from the leaves is used as an external application for psoriasis and painful swellings. The plants have been reported to have antiinflammatory, analgesic, antidiarrheal, antimicrobial, antioxidant, and insecticidal activities. Permission is granted to copy, distribute andor modify this document under the terms of the gnu free documentation license, version 1. The crude methanol extract of leucas aspera leaves showed strong 1,1diphenyl2picrylhydrazyl ddph and superoxide radicalscavenging activities compared to other polaritybased extracted fractions. Found throughout india, it is known for its various uses in the fields of medicine and agriculture. Plant tissue culture has paved way for the production of both pathogen free plants and secondary metabolites in large scale. Herbal medicines are having minimal adverse effects when compared to the available synthetic drugs to treat such chronic diseases and disorders. Mar 05, 2020 last update on medicinxl wikipedia, the free encyclopedia. Lipophilic extracts of leucas zeylanica, a multipurpose. The rats were housed in clean polypropylene cages and fed with commercial amruit rat feed and water ad libitum.
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